Children with complete data on the course of wheeze from birth to age 13 yrs (study population) | Children with incomplete data on the course of wheeze from birth to age 13 yrs | Children with complete data on the course of wheeze up to age 3 yrs, but with incomplete data on the course thereafter | |
Subjects n | 441 | 873 | 515 |
Data collected at birth | |||
Parental history of atopy | 240/440 (54.5) | 443/867 (51.1) | |
Male sex | 234/441 (53.1) | 450/873 (51.5) | |
Elevated cord blood IgE (≥0.9 kU·L−1) | 75/421 (17.8) | 166/840 (19.8) | |
≥1 older sibling | 194/441 (44.9) | 399/872 (45.8) | |
Parental smoking | 161/403 (39.9) | 411/787 (52.2)*** | |
Higher level of parental education | 240/422 (56.9) | 423/807 (52.4) | |
Data collected in the first years of life | |||
Early atopic dermatitis ≤2yrs | 108/441 (24.5) | 104/515 (20.2) | |
Early wheeze ≤3 yrs | 126/441 (28.6) | 173/515 (33.6) | |
Atopic sensitisation age 2 yrs (ImmunoCAP class I) | 67/283 (23.7) | 87/318 (27.4) | |
Breastfed ≥4 weeks | 347/439 (79.0) | 370/510 (72.5)* |
Data are presented as n/n total (%), unless otherwise stated. Ig: immunoglobulin. *: p<0.05 compared with children with complete data on the course of wheeze up to age 13 yrs; ***: p<0.001 compared with children with complete data on the course of wheeze up to age 13 yrs.