Table 1—

Baseline characteristics of study subjects

COPDControlsp-value
Subjects n1515
Age yrs60.9±1.460.7±1.40.919
Height m1.71±0.021.75±0.030.254
Weight kg78.7±3.181.1±2.60.553
BMI kg·m−227.0±1.126.5±0.90.735
FEV1 % pred46.4±3.7101.4±2.5<0.001
FEV1/VC53.5±2.879.0±1.0<0.001
VC % pred63.1±4.195.2±3.0<0.001
RV/TLC47.3±3.235.1±2.90.017
P0.1 kPa0.39±0.050.11±0.03<0.001
PI,max kPa5.64±0.648.41±0.950.026
Arterial pH7.38±0.017.38±0.010.797
Pa,CO2 mmHg42.0±0.9139.1±1.050.048
Pa,O2 mmHg76.5±2.382.5±2.80.112
Sa,O2 %94.5±0.595.3±0.50.284
Systolic blood pressure mmHg127.5±8.2135.6±7.60.476
Diastolic blood pressure mmHg62.8±3.568.7±3.40.244
fC beats·min−179.0±3.269.7±1.70.016
Respiratory rate breaths·min−116.2±1.116.9±0.70.603
Adrenaline ng·L−126.6±3.927.9±4.70.844
Noradrenaline ng·L−1222.6±16.0218.0±22.90.869
  • Data are presented as mean±sem, unless otherwise stated. COPD: chronic obstructive pulmonary disease; BMI: body mass index; FEV1: forced expiratory volume in one second; % pred: % predicted; VC: vital capacity; RV: residual volume; TLC: total lung capacity; P0.1: mouth occlusion pressure at 0.1 s; PI,max: maximal inspiratory pressure; Pa,CO2: arterial carbon dioxide tension; Pa,O2: arterial oxygen tension; Sa,O2: arterial oxygen saturation; fC: cardiac frequency. 1 mmHg = 0.133 kPa.