Non-OB | OB | |
Subjects | 35 | 14 |
Age yrs | 39±2.01 | 34.86±3.52 |
Sex | ||
Male | 20 | 4 |
Female | 15 | 10 |
Transplantation | ||
Single | 3 | 0 |
Bilateral | 32 | 14 |
Indication | ||
Cystic fibrosis | 23 | 8 |
Emphysema α1-antitrypsin | 7 | 1 |
Bronchiectasis | 1 | 1 |
Fibrosis | 1 | 1 |
Primary pulmonary hypertension | 0 | 2 |
Others | 2 | 1 |
FEV1 % pred | 84.29±3.22 | 38.07±3.53 |
Months after transplantation | 190.57±143.42 | 88.28±15.54 |
HLA-A, HLA-B, HLA-DR mismatch | ||
0–2 | 0 | 0 |
3–4 | 2 | 1 |
5–6 | 33 | 13 |
Cytomegalovirus mismatch (donor +/ recipient −) | 3 | 2 |
Treatment (if sampled) | ||
TAC, AZA | 7 | 0 |
CsA, AZA | 10 | 0 |
TAC, MMF | 5 | 0 |
CsA, MMF | 1 | 0 |
TAC, AZA, AZI | 2 | 4 |
TAC, MMF, AZI | 10 | 10 |
Pseudomonas aeruginosa colonisation status | ||
Pre-transplant colonisation | 24 | 8 |
Post-transplant re-colonisation | 19 | 8 |
Data are expressed as n or mean±se. OB: obliterative bronchiolitis; FEV1: forced expiratory volume in one second; % pred: % predicted; HLA: human leukocyte antigen; TAC: tacrolimus; AZA: azathioprine; CsA: cyclosporine; MMF: mycophenolate mofetil; AZI: azithromycin.