Comparison of bronchial inflammatory cells in chronic obstructive pulmonary disease patients with and without chronic bronchitis(CB)#
| With CB | Without CB | p-value | |
| Subjects n | 53 | 59 | |
| CD3+ lymphocytes | 124 (71–182) | 121 (60–193) | 0.95 |
| CD4+ lymphocytes | 45 (24–72) | 48 (28–75) | 0.61 |
| CD8+ lymphocytes | 18 (11–33) | 23 (9.0–42) | 0.48 |
| CD4/CD8 % | 2.04 (1.2–4.5) | 2.08 (1.2–3.8) | 0.96 |
| CD8/CD3 % | 0.16 (0.11–0.34) | 0.20 (0.11–0.31) | 1.00 |
| CD4/CD3 % | 0.37 (0.26–0.63) | 0.43 (0.25–0.74) | 0.51 |
| EG2+ cells | 1.0 (0.25–2.5) | 2.0 (1.0–5.5) | 0.019* |
| Neutrophils | 3.0 (2.0–5.5) | 5.5 (2.0–8.5) | 0.080 |
| Plasma cells | 8.0 (3.5–15) | 9.0 (4.0–14.5) | 0.34 |
| CD68+ cells | 8.5 (4.3–11.8) | 10 (5.0–14) | 0.20 |
| AA1+ cells | 27 (21–34) | 26 (18–35) | 0.80 |
Data are presented as median (interquartile range) of bronchial inflammatory cells (per 0.1 mm2 of sub-epithelial area), unless otherwise stated. EG2: eosinophils. #: data from one patient was excluded as the biopsy specimens were not adequate for analysis. *: p<0.05.