0 h | 24 h | 48 h | 72 h | 96 h | p-value# | |
Temperature °C | 36.4±0.7 | 40.1±0.7 | 39.0±1.2 | 39.0±1.7 | 39.1±1.7 | 0.032 |
Cardiac frequency bpm | 146±36 | 156±39 | 138±11 | 141±20 | 140±29 | 0.35 |
Mean Pa,O2 mmHg | 124±4 | 114±19 | 123±22 | 118±21 | 108±27 | 0.58 |
CL,s mL·cmH20−1 | 16.9±3.1 | 16.4±3.2 | 14.8±3.9 | 13.8±4.0 | 13.2±3.2 | 0.14 |
Pa,O2/FI,O2mmHg | 350±144 | 210±98 | 150±52 | 138±50 | 132±41 | 0.017 |
Haematocrit L·L−1 | 30±1 | 29±2 | 27±3 | 25±1 | 22±1 | 0.06 |
WBC count ×109 cells·L−1 | 18160±10046 | 21920±12934 | 13160±3922 | 10820±5140 | 12340±4160 | 0.09 |
Creatinine mg·dL−1 | 0.6±0.1 | 1.1±0.8 | 0.6±0.3 | 0.4±0.1 | 0.4±0.1 | 0.52 |
Bilirubin mg·dL−1 | 0.4±0.1 | 0.3±0.2 | 0.3±0.2 | 0.3±0.1 | 0.3±0.1 | 0.83 |
ASAT U·dL−1 | 61±46 | 177±285 | 255±229 | 192±269 | 130±146 | 0.78 |
ALAT U·dL−1 | 46±15 | 64±42 | 69±56 | 79±81 | 70±62 | 0.99 |
CRP mg·dL−1 | 2.9±1.7 | 4.9±3.9 | 5.5±3.5 | 3.7±0.9 | 3.6±2.2 | 0.71 |
Data are presented as mean±sd, unless otherwise stated. bpm: beats per minute; Pa,O2: arterial oxygen tension; CL,s: static lung compliance; FI,O2: inspiratory fraction; WBC: white blood cell; ASAT: aspartate amine transferase; ALAT: alanine amine transferase; CRP: C-reactive protein. #: calculated according to the Friedman test. 1 mmHg = 0.133 kPa.