Hospitalisation rates and estimated total winter excess hospitalisation among adults associated with influenza virus and respiratory syncytial virus(RSV)
| Weekly incidence per 100000 population | Total winter excess per 100000 population# | |||||||
| Period of influenza virus- predominance | Period of RSV- predominance | Summer baseline period | Peri-seasonal baseline period | Influenza virus | RSV | |||
| versus summer baseline period | versus peri- seasonal baseline period | versus summer baseline period | versus peri-seasonal baseline period | |||||
| URTIs | ||||||||
| 18–49 yrs | ||||||||
| nonhigh-risk | 0.6 | 0.4 | 0.4 | 0.5 | 1.2 (0.9–1.4) | 0.5 (0.3–0.8) | 0.2 (0.0–0.4) | None¶ |
| high-risk | 0.4 | 0.4 | 0.3 | 0.3 | 0.9 (0.3–1.6) | 0.7 (0.0–1.3) | 0.5 (-0.1–1.2)+ | 0.2 (-0.4–0.9)+ |
| 50–64 yrs | ||||||||
| nonhigh-risk | 0.7 | 0.6 | 0.5 | 0.6 | 2.1 (1.7–2.7) | 1.4 (0.8–1.9) | 0.8 (0.3–1.2) | None¶ |
| high-risk | 0.8 | 0.7 | 0.4 | 0.6 | 3.2 (2.4–4.2) | 2.1 (1.2–3.0) | 1.9 (1.1–2.6) | 0.7 (-0.2–1.5)+ |
| ≥65 yrs | 2.0 | 1.6 | 1.0 | 1.2 | 8.9 (8.1–9.6) | 6.7 (5.9–7.5) | 5.2 (4.5–5.9) | 3.2 (2.5–3.9) |
| LRTIs and PDs | ||||||||
| 18–49 yrs | ||||||||
| nonhigh-risk | 2.5 | 2.2 | 2.0 | 2.3 | 4.2 (3.7–4.7) | 2.1 (1.5–2.6) | 1.7 (1.2–2.2) | None¶ |
| high-risk | 14.2 | 13.1 | 13.3 | 11.3 | 23.7 (19.8–27.6) | 6.8 (2.7–10.9) | 13.6 (9.9–17.2) | None¶ |
| 50–64 yrs | ||||||||
| nonhigh-risk | 6.0 | 5.0 | 4.4 | 5.1 | 12.8 (11.3–14.3) | 7.0 (5.5–8.6) | 4.3 (2.9–5.6) | None¶ |
| high-risk | 24.5 | 22.3 | 16.5 | 20.3 | 66.5 (61.6–71.4) | 34.9 (29.9–40.0) | 44.2 (39.7–48.7) | 15.0 (10.2–19.7) |
| ≥65 yrs | 38.4 | 34.8 | 24.5 | 30.0 | 115.2 (111.6–118.8) | 69.1 (65.4–72.9) | 79.7 (76.4–83.0) | 37.0 (33.5–40.4) |
| Cardiovascular complications | ||||||||
| 18–49 yrs | ||||||||
| nonhigh-risk | 3.5 | 3.4 | 3.3 | 3.5 | 1.7 (1.0–2.2) | 0.3 (−0.4–0.9)+ | 0.9 (0.3–1.5) | None¶ |
| high-risk | 9.6 | 8.9 | 8.9 | 9.1 | 6.2 (3.0–9.6) | 4.3 (1.0–7.6) | 0.2 (−2.9–3.2)+ | None¶ |
| 50–64 yrs | ||||||||
| nonhigh-risk | 31.0 | 29.1 | 28.3 | 30.0 | 21.7 (18.2–25.2) | 8.3 (4.7–11.9) | 5.5 (2.2–8.8) | None¶ |
| high-risk | 34.3 | 32.3 | 31.3 | 33.0 | 24.9 (18.9–31.0) | 10.8 (4.6–16.9) | 7.2 (1.5–12.8) | None¶ |
| ≥65 years | 87.2 | 84.6 | 77.5 | 83.3 | 81.1 (75.5–86.7) | 32.5 (26.6–38.2) | 55.1 (49.8–60.5) | 10.0 (4.5–15.5) |
| Other | ||||||||
| 18–49 yrs | ||||||||
| nonhigh-risk | 0.6 | 0.5 | 0.5 | 0.5 | 0.2 (−0.1–0.4)+ | 0.3 (0.1–0.5) | None¶ | None¶ |
| high-risk | 0.7 | 0.6 | 0.6 | 0.6 | 0.5 (−0.3–1.4)+ | 0.9 (0.1–1.8) | 0.2 (−0.6–1.0)+ | 0.5 (−0.2–1.4)+ |
| 50–64 yrs | ||||||||
| nonhigh-risk | 1.5 | 1.4 | 1.3 | 1.4 | 1.4 (0.7–2.2) | 1.0 (0.2–1.7) | 0.6 (-0.2–1.5)+ | 0.2 (-0.5–1.0)+ |
| high-risk | 1.2 | 0.8 | 0.9 | 0.9 | 2.2 (1.2–3.3) | 2.1 (0.8–3.2) | None¶ | None¶ |
| ≥65 years | 3.7 | 3.4 | 3.3 | 3.4 | 2.8 (1.7–4.0) | 2.7 (1.5–3.8) | 0.6 (−0.5–1.7)+ | 0.5 (−0.6–1.5)+ |
Data are presented as mean (95% confidence interval), unless otherwise stated. URTI: upper respiratory tract infection; LRTI: lower respiratory tract infection; PD: pulmonary disease. #: total winter excess was calculated as the difference between rates during virus active periods and reference periods multiplied by the average number of virus active weeks per winter, i.e. 8.3 weeks for influenza virus and 7.7 weeks for RSV; ¶: no nonsignificant excess; +: nonsignificant excesses.