Table 5—

Cochrane meta-analysis of effect of nicotine replacement therapy (NRT) formulations

Smoking cessation therapy	NRT versus placebo	Abstinence rate
Smoking cessation therapy	NRT versus placebo	NRT	Control
All NRT formulations	1.77 (1.7–1.9)	17	10
Nicotine gum	1.66 (1.5–1.8)	17
Nicotine patch	1.81 (1.6–2.0)	14
Nicotine inhaler	2.14 (1.4–3.2)	17
Nicotine nasal spray	2.35 (1.6–3.4)	24
Nicotine sublingual tablet/lozenge	2.05 (1.9–3.3)	17
4 mg gum *versus* 2 mg gum	2.20 (1.5–3.3)
*Fixed gum versus* ad libitum gum**	1.29 (0.90–1.9)
Combination of two NRT *versus* single NRT	1.42 (1.1–1.8)
Bupropion SR^#	2.06 (1.8–2.4)

Data are presented as odds ratio (95% confidence interval) or %. Total number of subjects in analysis n = 39,503. SR: sustained release. Data are taken from 140 except ^#, taken from 141.