Comparison of different methods of assessing adrenal function: subjects with an abnormal response versus mean area under the curve (AUC) and mean peak cortisol level post-stimulation
| First author [ref.] | Doses μg·day-1 | Subjects n | Abnormal cortisol peak# or change¶ post-stimulation | Abnormal cortisol peak# post-stimulation | AUC μg·dL-1·h | Peak μg·dL-1 |
| Kellerman 19 | 0 | 20 | 0 (0) | 0 (0) | 198.2 | 30.3 |
| 500 | 21 | 0 (0) | 0 (0) | 180.9 | 27.6 | |
| 1000 | 20 | 2 (10.0) | 2 (10.0) | 157.4 | 24.1 | |
| 1500 | 19 | 3 (15.8) | 3 (15.8) | 147.8 | 22.9 | |
| 2000 | 17 | 2 (11.8) | 2 (11.8) | 143.0 | 22.9 | |
| Pred | 21 | 6 (28.6) | 6 (28.6) | 124.0 | 19.7 | |
| Sorkness A 20 | 0 | 30 | 0 (0) | 0 (0) | 215.5±5.2 | 32.7±0.9 |
| 200 | 26 | 0 (0) | 0 (0) | 224.4±4.8 | 33.7±0.7 | |
| 1000 | 29 | 0 (0) | 0 (0) | 207.2±6.2 | 30.6±0.9 | |
| Pred | 27 | 4 (14.8) | 3 (11.1) | 156.4±7.9 | 24.5±1.3 | |
| Sorkness B 20 | 0 | 29 | 0 (0) | 0 (0) | 202±5.5 | 31.1±1.0 |
| 200 | 26 | 0 (0) | 0 (0) | 202.7±5.6 | 30.7±0.9 | |
| 500 | 28 | 0 (0) | 0 (0) | 202.3±7.0 | 30.3±1.1 |
Data are presented as n (%) or mean±sem, unless otherwise stated. Pred: prednisone. #: <18 μg·dL-1; ¶: <7 μg·dL-1.