Never-smokers | Ex-smokers | p-value# | Current smokers | p-value# | |
Subjects n | 111 | 75 | 35 | ||
FeNO,0.05 ppb | 22.8 (20.3–25.7) | 17.7 (15.7–20.1) | 0.02 | 14.0 (11.2–17.6) | <0.001 |
Caw,NO ppb | 126 (114–140) | 110 (97–124) | 0.26 | 79.0 (63.0–99.0) | <0.001 |
Daw,NO mL·s-1 | 9.28 (8.42–10.2) | 7.95 (6.99–9.05) | 0.18 | 8.87 (7.05–11.2) | 0.92 |
CA,NO ppb | 1.32 (1.13–1.54) | 1.41 (1.14–1.73) | 0.88 | 0.93 (0.67–1.28) | 0.12 |
J'aw,NO pL·s-1 | 1153 (1011–1315) | 858 (745–989) | 0.02 | 688 (529–893) | 0.001 |
Data are presented as geometric mean (95% confidence interval), unless otherwise stated. FeNO,0.05: fractional exhaled nitric oxide concentration at a flow rate of 50 mL·s-1; Caw,NO: airway tissue nitric oxide concentration; Daw,NO: airway transfer factor (or diffusing capacity) for nitric oxide; CA,NO: alveolar nitric oxide concentration; J'aw,NO: maximum total airway nitric oxide flux. #: versus never-smokers.