Table 1—

Exhaled nitric oxide variables in never-, ex- and current smokers

Never-smokersEx-smokersp-value#Current smokersp-value#
Subjects n1117535
FeNO,0.05 ppb22.8 (20.3–25.7)17.7 (15.7–20.1)0.0214.0 (11.2–17.6)<0.001
Caw,NO ppb126 (114–140)110 (97–124)0.2679.0 (63.0–99.0)<0.001
Daw,NO mL·s-19.28 (8.42–10.2)7.95 (6.99–9.05)0.188.87 (7.05–11.2)0.92
CA,NO ppb1.32 (1.13–1.54)1.41 (1.14–1.73)0.880.93 (0.67–1.28)0.12
J'aw,NO pL·s-11153 (1011–1315)858 (745–989)0.02688 (529–893)0.001
  • Data are presented as geometric mean (95% confidence interval), unless otherwise stated. FeNO,0.05: fractional exhaled nitric oxide concentration at a flow rate of 50 mL·s-1; Caw,NO: airway tissue nitric oxide concentration; Daw,NO: airway transfer factor (or diffusing capacity) for nitric oxide; CA,NO: alveolar nitric oxide concentration; J'aw,NO: maximum total airway nitric oxide flux. #: versus never-smokers.