COPD smokers | Non-COPD smokers | Asthma¶ | Normal subjects | |||||
Mild | Moderate | Severe | Very severe | Overall | ||||
Subjects n | 6 | 15 | 26 | 16 | 63 | 60 | 36 | 30 |
Age yrs | 55±12 | 64±9 | 73±7 | 69±8 | 68±10*** | 59±15 | 50±12 | 56±17 |
Smoking+ pack-yrs | 35±5 | 50±21 | 50±15 | 55±12 | 48±25 | Nonsmokers | Nonsmokers | |
FEV1 % pred | 88±8 | 60±8 | 41±5 | 23±4 | 49.3±17.0§ | 85±25 | 78±19 | 92±4 |
FVC % pred | 102±7 | 85±16 | 66±14 | 44±10 | 69±22§ | 88±10 | 95±20 | 88±4 |
FEV1/FVC | 70±3 | 60±13 | 55±17 | 38±6 | 62±18§ | 82±8 | 80±10 | 83±8 |
Data are presented as mean±sd, unless otherwise stated. FEV1: forced expiratory volume in one second; % pred: percentage of the predicted value; FVC: forced vital capacity. #: four severity groups; ¶: mild; +: cumulative cigarette consumption. ***: p<0.001; §: p<0.0001 (ANOVA between the four groups; COPD taken as one group).