Table 3—

Individual predictors for treatment outcomes in multidrug-resistant patients who underwent surgical lung resection

Success groupFailure groupp-value
Subjects n5722
Age yrs35±1432±100.890
Male36 (63.1)12 (54.5)0.482
BMI <18.5 kg·m-215 (26.3)10 (45.4)0.101
Primary drug resistance6 (10.5)17 (77.3)<0.001
<5 drugs used pre-operatively5 (8.8)4 (7.1)0.238
>1 yr of pre-operative treatment47 (82.4)16 (72.2)0.335
Quinolone used pre-operatively50 (87.7)20 (90.9)0.689
Resistance to ofloxacin4 (7.0)6 (27.3)0.015
Resistance to injectables18 (31.6)6 (27.3)0.709
Number of resistant drugs >528 (49.1)8 (36.4)0.307
Multilobar involvement54 (94.7)22 (100)0.273
Pre-operative positive M. tuberculosis culture55 (96.5)22 (100)0.360
Presence of cavitary lesion55 (96.5)22 (100)0.360
Presence of cavity beyond the range of resection11 (19.3)17 (77.3)<0.001
Growth of M. tuberculosis >200 colonies51 (89.5)20 (90.9)0.850
Pleuro-pneumonectomy13 (22.8)4 (7.1)0.654
  • Data are presented as mean±sd or n (%), unless otherwise stated. BMI: body mass index; M. tuberculosis: Mycobacterium tuberculosis.