Relationships between colds and exacerbation frequency in chronic obstructive pulmonary disease#
| Validated definition | Alternative definition | |||||
| Infrequent exacerbators | Frequent exacerbators | p-value | Infrequent exacerbators | Frequent exacerbators | p-value | |
| Exacerbation frequency ·yr−1 | 1.55 (0.81–2.16) | 3.83 (3.21–5.31) | 1.31 (0.76–2.02) | 3.45 (2.90–3.45) | ||
| Total colds frequency ·yr−1 | 0.94 (0.44–1.75) | 1.73 (0.88–3.73) | 0.003 | 0.95 (0.45–1.75) | 1.73 (0.78–3.39) | 0.016 |
| Upper airway colds frequency ·yr−1 | 0.44 (0.00–0.94) | 0.74 (0.00–2.10) | 0.131 | 0.63 (0.15–1.46) | 0.92 (0.30–2.56) | 0.172 |
| Exacerbations associated with a cold ·yr−1 | 0.45 (0.00–0.88) | 0.95 (0.46–1.63) | <0.001 | 0.32 (0.00–0.54) | 0.55 (0.00–1.08) | <0.001 |
| Colds associated with exacerbation/total colds ratio % | 50 (11–80) | 54 (33–80) | 0.135 | 33 (3–50) | 33 (17–60) | 0.133 |
Data are presented as median (interquartile range), unless otherwise stated. #: each group n = 75.