Potentially vasoactive genes and their regulation by corticosteroids in vascular smooth muscle and endothelial cells
| Upregulation | Downregulation | |||
| Vascular smooth muscle cells | α1β-Adrenergic receptor 177 | Na+/Ca2+ ATPase 178 | ||
| AT1 receptor 179 | Ca2+-activated K+ channel 180 | |||
| Vasopressin V1A receptor 181 | ||||
| NPR-A 182 | ||||
| ACE 183 | ||||
| Preproendothelin-1 184 | ||||
| Na+/K+ ATPase 185 | ||||
| Endothelial cells | ACE 186 | eNOS 187 | ||
| CAT-1 188 | ||||
| Phospholipase A2 189 | ||||
| COX-2 190 | ||||
AT1: angiotensin II type 1; NPR: natriuretic peptide receptor; ACE: angiotensin-converting enzyme; eNOS: endothelial nitric oxide synthase; CAT-1: cationic amino acid transporter-1; COX-2: cyclooxygenase type 2.