Table. 1—

Grades of recommendation(ranging from A1 to C4)

Grades of recommendation
 AConsistent evidence = clear outcome
 BInconsistent evidence = unclear outcome
 CInsufficient evidence = consensus
Suffix for recommendations
 Preventative and therapeutic intervention studies#
  1SR or MA of RCTs
  21 RCT or >1 RCT, but no SR or MA
  31 cohort study or >1 cohort study, but no SR or MA
  4Other
 Diagnostic, prognostic, aetiological and other types of studies
  1SR or MA of cohort studies
  21 cohort study or >1 cohort study, but no SR or MA
  3Other
  • SR: systematic review; MA: meta-analysis; RCT: randomised controlled trial. #: including harm.