n | Prev % | Ever asthma | Bronchial hyperreactivity# | |||||
Sens | Spec | PPV¶ | Sens | Spec | PPV¶ | |||
Wheeze | ||||||||
Wheeze | 2443 | 22 | 0.63 | 0.82 | 0.29 | 0.47 | 0.82 | 0.22 |
Wheeze, breathlessness | 1209 | 11 | 0.48 | 0.92 | 0.45 | 0.31 | 0.93 | 0.29 |
Wheeze, breathlessness, no cold | 808 | 7 | 0.38 | 0.95 | 0.53 | 0.24 | 0.95 | 0.33 |
Bronchial hyperresponsiveness | ||||||||
Slope >25% | 2815 | 25 | 0.64 | 0.78 | 0.26 | |||
>20% at 1 mg | 1538 | 14 | 0.52 | 0.90 | 0.38 | § | § | § |
Slope >10% | 1129 | 10 | 0.42 | 0.93 | 0.42 | |||
Wheeze and BHR# | ||||||||
Wheeze, BHR | 725 | 6.4 | 0.40 | 0.96 | 0.62 | |||
Wheeze, breathlessness, BHR | 481 | 4.3 | 0.32 | 0.98 | 0.75 | § | § | § |
Wheeze, breathlessness, no cold, BHR | 366 | 3.2 | 0.26 | 0.99 | 0.81 | |||
ECRHS definition+ | ||||||||
Any 1 of 3 variables | 849 | 7.5 | 0.25 | 0.95 | 0.34 | |||
Any 2 of 3 variables | 286 | 2.5 | § | § | § | 0.14 | 0.99 | 0.99 |
All 3 variables | 117 | 1.0 | 0.06 | 1.00 | 0.59 | |||
Score | ||||||||
Any 1 of 8 questions | 3719 | 32.9 | 0.60 | 0.71 | 0.18 | |||
Any 2 of 8 questions | 1679 | 14.9 | 0.40 | 0.89 | 0.27 | |||
Any 3 of 8 questions | 937 | 8.3 | 0.28 | 0.95 | 0.34 | |||
Any 4 of 8 questions | 538 | 4.8 | § | § | § | 0.20 | 0.98 | 0.98 |
Any 5 of 8 questions | 344 | 3.0 | 0.15 | 0.99 | 0.50 | |||
Any 6 of 8 questions | 212 | 1.9 | 0.11 | 0.99 | 0.56 | |||
Any 7 of 8 questions | 115 | 1.0 | 0.06 | 1.00 | 0.59 | |||
All 8 questions | 43 | 0.4 | 0.02 | 1.00 | 0.63 |
Data are presented as n, unless otherwise stated. Prev: prevalence; BHR: bronchial hyperresponsiveness; ECRHS: European Community Respiratory Health Study. #: >20% fall in FEV1 at 1 mg; ¶: theoretical PPV, if true prevalence of asthma 10%; +: woken by shortness of breath, attack of asthma or asthma medication; §: part of the definition.