Table. 3—

Mean fluorescence intensity values of the surface receptors studied in peripheral blood monocytes (PBM) and alveolar macrophages (AM)

NonsmokersSmokers
Normal lung functionCOPD
PBMAMPBMAMPBMAM
Subjects n91418
CD361528±237##13±41713±387##21±71695±188##13±3
CD5123±818±326±1322±316±618±3
CD6189±12##8±2231±59##16±3119±31##10±2
CD14474±21##36±7544±37##50±17502±33##25±6
CD441286±411371±1021151±591305±481165±421199±74
HLA-DR35±446±537±744±429±328±2**
CD801.2±0.7##39±41±0.1##38±61±0.2##19±4**
CD8629±3##248±1628±4##253±1425±2##220±19
CD4013±2##305±2621±6##326±2721±4##291±28
CD11b685±49##39±9731±44##52±6719±38##49±6
  • Data presented as mean±sem. COPD: chronic obstructive pulmonary disease; HLA: human leukocyte antigen. **: p<0.01 with respect to nonsmokers and smokers with normal lung function; ##: p<0.01 within groups (PBM versus AM).