Table 3—

Mean respiratory tract symptom scores per day in children during weeks of illness

All weeks of illnessInfluenza-positive weeks
VaccinePlacebop-valueVaccinePlacebop-value
Outcomes n1761662220
Upper respiratory tract
 Runny or stuffy nose0.910.850.430.970.850.60
 Sneezing0.330.290.440.440.380.60
 Burning or watery eyes0.130.150.740.260.200.68
 Sore throat0.380.350.520.320.450.24
 Hoarseness0.120.120.980.060.150.21
 Fever or shivering0.220.210.860.410.430.82
 Headache0.390.330.300.370.540.27
 Myalgia0.070.070.890.070.100.67
 Total symptom score2.562.370.372.913.130.69
Lower respiratory tract
 Cough during the day0.931.030.261.051.270.39
 Cough during the night0.500.520.780.670.710.86
 Wheeze during the day0.130.160.500.150.180.77
 Wheeze during the night0.100.110.580.070.110.50
 Difficult breathing or shortness of breath0.390.420.560.320.640.06
 Total symptom score2.052.240.332.252.910.24
  • Each separate score ranged from 0 (absent) to 3 (severe).