Table 1—

Baseline characteristics of the study population

VaccinePlacebo
At inclusion visits n347349
 Age yrs10.5±3.210.6±3.3
 Females %48.143.6
 Age of onset of asthma yrs3.5±3.83.3±3.4
 Ever vaccinated for influenza %53.656.7
 History of allergy %73.566.1
 Child born in the Netherlands %97.798.9
 FEV1 % predicted89.5±16.188.9±16.0
At baseline visits
 Quality of life n331331
  Total score6.166.16
  Activities5.605.60
  Emotions6.636.63
  Symptoms6.056.05
 Spirometry n332337
  FEV1
   Mean2.13±0.762.13±0.80
   % predicted93±1492±13
  FVC
   Mean2.43±0.882.43±0.96
   % predicted92±1490±14
  MEF50
   Mean2.68±1.102.66±1.0
   % predicted90±2590±24
  MEF25
   Mean1.42±0.711.42±0.67
   % predicted94±3696±36
  • Data are presented as mean±sd unless otherwise stated. FEV1: forced expiratory volume in one second; FVC: forced vital capacity; MEF50: Maximum expiratory flow at 50% FVC; MEF25: maximum expiratory flow at 25% of FVC. : mean of scores ranging from 1–7, with higher scores indicating better quality of life.