Probability of interstitial lung disease (ILD) as a function of lymphocytes and CD4/CD8 in the group with suspected ILD
| Lymphocytes % and CD4/CD8 ratio# | Subjects n | A priori | A posteriori | |||||
| <30 | 30–50 | >50 | ||||||
| Low | High | Low | High | Low | High | |||
| Sarcoidosis | 239 | 33.7 | 21.0*** | 72.2*** | 45.8* | 75.5*** | 29.8 | 51.7* |
| UIP | 112 | 15.8 | 22.3* | 11.1 | 6.0* | 1.9* | 2.1* | 0.0 |
| EAA | 66 | 9.3 | 2.3*** | 1.9 | 22.9* | 13.2 | 42.6*** | 31.0* |
| NSIP | 46 | 6.5 | 7.0 | 5.6 | 6.0 | 1.9 | 10.6 | 3.5 |
| Connective tissue disease | 18 | 2.5 | 2.7 | 0.0 | 2.4 | 0.0 | 4.3 | 6.9 |
| Others | 229 | 32.3 | 44.8*** | 9.3*** | 16.9* | 7.6* | 10.6* | 6.9* |
| Total n | 710 | 444 | 54 | 83 | 53 | 47 | 29 | |
Data are presented as %, unless otherwise stated. UIP: usual interstitial pneumonia; EAA: extrinsic allergic alveolitis; NSIP: nonspecific interstitial pneumonia. *: p<0.05; ***: p<0.001 versus the respective a priori value. #: low (CD4/CD8 <3.5)