Probability of interstitial lung disease (ILD) as a function of CD4/CD8 in suspected ILD
| CD4/CD8 ratio | Subjects n | A priori | A posteriori | |||
| No value# | <0.5 | 0.5–3.5 | >3.5 | |||
| Sarcoidosis | 239 | 33.7 | 16.3*** | 9.1* | 40.3 | 69.1*** |
| UIP | 112 | 15.8 | 22.7* | 13.6 | 12.2 | 5.2* |
| EAA | 66 | 9.3 | 1.5*** | 27.3* | 17.2* | 12.5 |
| NSIP | 46 | 6.5 | 7.6 | 18.2 | 5.4 | 3.7 |
| Connective tissue disease | 18 | 2.5 | 2.7 | 0.0 | 3.2 | 1.5 |
| Others | 229 | 32.2 | 49.2*** | 31.8 | 21.7* | 8.1*** |
| Total n | 710 | 331 | 22 | 221 | 136 | |
Data are presented as %, unless otherwise stated. UIP: usual interstitial pneumonia; EAA: extrinsic allergic alveolitis; NSIP: nonspecific interstitial pneumonia. *: p<0.05; ***: p<0.001 versus the respective apriori value; #: not measurable due to low lymphocyte numbers