Control | ARDS all patients | Primary ARDS | Secondary ARDS | |
Subjects n | 20 | 40 | 31 | 9 |
Age yrs | 28.1±1.3 | 54.3±2.3*** | 55.9±2.8*** | 48.9±3.3*** |
Sex F/M | 10/10 | 17/23 | 13/18 | 4/5 |
Pa,O2/FI,O2 mmHg | 455.1±15.1 | 143.0±9.0*** | 134.0±9.1*** | 170.2±22.2*** |
Patients alive on day 28 | 30 (75.0) | 23 (74.2) | 7 (77.8) | |
BALF recovery % | 79.7±2.2 | 58.8±2.5*** | 57.1±2.6*** | 64.1±6.1* |
Neutrophils % | 1.1±0.2 | 55.2±4.3*** | 54.0±5.6*** | 59.0±4.7*** |
Lymphocytes % | 4.4±0.7 | 8.8±2.5 | 10.3±3.3 | 4.2±1.1 |
Macrophages % | 94.5±0.6 | 36.0±3.5*** | 35.7±4.5*** | 36.8±4.9*** |
PL µg·ml−1 | 31.8±3.7 | 27.2±2.8 | 25.4±3.3 | 33.2±5.4 |
Protein mg·ml−1 | 0.07±0.00 | 1.04±0.12*** | 1.09±0.21*** | 0.94±0.32*** |
PPQ | 0.460±0.028 | 0.042±0.009*** | 0.035±0.007*** | 0.063±0.029*** |
Data are presented as n, mean±sem and n (%). Acute respiratory distress syndrome (ARDS) patients were further divided into primary and secondary ARDS. F: female; M: male; Pa,O2: arterial oxygen tension; FI,O2: inspiratory oxygen fraction; BALF: bronchoalveolar lavage fluid; PL: total phospholipids in BALF; protein: total protein in BALF; PPQ: phospholipid-protein ratio. *: p<0.05; ***: p<0.001. 1 kPa=0.133 mmHg