Table 3—

Comparison of absolute metabolite concentrations between obstructive sleep apnoea (OSA) patients and controls

OSA patientsControlsp-value
Subjects n2210
PWM
 Cho1.80±0.351.98±0.430.26
 Cr4.91±0.645.14±0.840.45
 NAA7.52±1.017.56±1.060.97
 mI5.48±0.745.8±0.930.26
FWM
 Cho1.75±0.332.18±0.440.017
 Cr5.03±0.695.18±0.640.6
 NAA6.76±1.067.68±1.060.04
 mI5.53±1.386.16±1.170.18
PFC
 Cho1.41±0.261.57±0.350.25
 Cr5.55±0.565.66±0.720.57
 NAA7.32±0.817.6±0.750.36
 mI5.86±0.995.6±0.970.34
  • Data are expressed in mmol per kg and presented as mean±sd. PWM: parieto-occipital white matter; FWM: frontal white matter; PFC: prefrontal cortex; Cho: choline; Cr: creatine; NAA: N-acetylaspartate; mI: myo-inositol.