Mild/moderate COPD | Control smokers | Control nonsmokers | p‐value | |
Ly·mL−1×103 | 11 (3–101) | 5.2 (1.4–7.1) | 4.1 (0.9–17) | 0.30 |
Ly % | 4 (1–35) | 1.9 (0.8–3.8) | 4.3 (0.9–12) | 0.077 |
STAT4+ Ly·mL−1×103 | 6.7 (1.9–9.8)* | 2.3 (0–4.1) | 1.2 (0.3–5.1) | 0.017 |
Phospho‐STAT4+ Ly·mL−1×103 | 2.8 (0.2–5.9)* | 1.03 (0.09–1.6) | 0.69 (0–2.3) | 0.012 |
T‐bet+ Ly·mL−1×103 | 1.5 (0–7.1) | 0.6 (0–1.1) | 0.49 (0–2.99) | 0.21 |
IFN‐γ+ Ly·mL−1×103 | 2.5 (0.3–5) | 1.2 (0.4–2.1) | 0.9 (0.24–7.9) | 0.43 |
STAT4+ Ly % | 60 (6–68) | 60 (0–80) | 30 (8–57) | 0.14 |
Phospho‐STAT4+ Ly % | 27 (3–68) | 17 (3–74) | 18 (0–42) | 0.65 |
T‐bet+ Ly % | 10 (0–45) | 15 (0–33) | 12 (0–73) | 0.96 |
IFN‐γ+ Ly % | 25 (4–36) | 30 (14–35) | 23 (10–57) | 0.64 |
Data are presented as median (range), unless otherwise stated
STAT4: signal transducer and activator of transcription 4
COPD: chronic obstructive pulmonary disease
*: p<0.05, significantly different from control smokers and control nonsmokers