Subjects n | Age yrs | Sex M/F | Smoking history pack-yrs | FEV1 % pred | FEV1/FVC % | ΔFEV1 post-salbutamol % baseline | |
Control nonsmokers | 7 | 58±7 | 4/3 | 0 | 118±17 | 87±7 | |
Control smokers | 7 | 56±10 | 5/2 | 28±10 | 104±18 | 81±6 | |
Mild/moderate COPD | 8 | 69±5** | 8/0 | 40±15 | 71±8** | 67±7** | 4±4 |
Data are expressed as n and mean±sd
COPD: chronic obstructive pulmonary disease
M: male
F: female
FEV1: forced expiratory volume in one second
FVC: forced vital capacity
**: p<0.01, significantly different from control smokers and control nonsmokers