Subjects n | Age yrs | Sex M/F | Smoking history pack-yrs | FEV1 % pred | FEV1/FVC % | ΔFEV1 post-salbutamol % baseline | |
Control nonsmokers | 12 | 61±11 | 6/6 | 0 | 111±14 | 85±5 | |
Control smokers | 14 | 60±6 | 12/2 | 39±23 | 106±12 | 82±6 | |
Mild/moderate COPD | 12 | 64±9 | 10/2 | 46±30 | 59±16# | 57±8# | 4±4 |
Data are presented as n or mean±sd
COPD: chronic obstructive pulmonary disease
M: male
F: female
FEV1: forced expiratory volume in one second
FVC: forced vital capacity
#: p<0.0001, significantly different from control smokers and control nonsmokers