Healthy elderly controls | COPD patients | |
Subjects n | 39 | 36 |
Age yrs | 65±9 | 67±8 |
Weight kg | 71±8 | 69±16 |
Height cm | 166±5 | 165±5 |
BMI kg·m−2 | 25.7±2.6 | 25.2±5.8 |
FEV1 % pred | 92±7 | 36±14** |
FEV1/FVC % | 72±4 | 46±10** |
TLC % pred | 88±15 | 113±30 |
DL,CO % pred | 90±18 | 64±25** |
Pa,O2 mmHg | nd | 64±11 |
Pa,CO2 mmHg | nd | 47±8 |
PI,max cmH2O | −110±40 | −39±24** |
PI,max % pred | 117±35 | 38±21** |
HGSnon-dom % pred | 90±14 | 77±12** |
HGSdom % pred | 87±24 | 77±19* |
Daily physical activity au | 16.3±9.8 | 13.1±6.2* |
Data are presented as mean±sd unless otherwise indicated
COPD: chronic obstructive pulmonary disease
BMI: body mass index
FEV1: forced expiratory volume in one second
FVC: forced vital capacity
TLC: total lung capacity
DL,CO: CO diffusing capacity of the lung
Pa,O2: arterial O2 tension
Pa,CO2: CO2 arterial tension
PI,max: maximal inspiratory pressure
HGSnon: nondominant hand grip strength
HGSdom: dominant hand grip strength
au: arbitrary units as in Voorrips et al. 20
nd: not determined
*: p<0.05
**: p<0.01