Table 4—

Single antibiotic susceptibility results presented as minimal inhibitory concentration (MIC) log2 values for the biofilm grown isolates obtained from cystic fibrosis patients

AntibioticMICs for isolatesp-values
SputumBALPSBSputum versus BALSputum versus PSB
Tobramycin6.0±0.06.0±0.06.0±0.00.990.99
Meropenem5.0±0.05.0±0.05.0±0.00.990.99
Amikacin7.0±0.07.0±0.07.0±0.00.990.99
Ceftazidime8.0±0.08.0±0.08.0±0.00.990.99
Piperacillin8.0±0.08.0±0.08.0±0.00.990.99
Ciprofloxacin3.93±0.233.87±0.213.80±0.40.370.10
  • MIC values (mean±sd) were obtained from paired t-test analysis and are shown as log2 values of the dilution used

  • n=12

  • Comparative p-values are derived from the generalised estimating equations model

  • BAL: bronchoalveolar lavage

  • PSB: protected specimen brush