Transaminase activity, liver and spleen weight, and portal venous pressure (PVP) in sham-operated rats, and untreated and pentoxifylline (PTX)-treated cirrhotic rats#
| Sham-operated | Cirrhotic | ||
| Untreated | PTX-treated | ||
| AST IU·L−1 | 62±4 | 174±23* | 144±7* |
| ALT IU·L−1 | 25±2 | 54±9* | 43±3* |
| Liver weight g | 14±0.5 | 27±1* | 25±1* |
| Spleen weight g | 1.3±0.1 | 3.5±0.4* | 2.7±0.2* |
| PVP mmHg | 4.2±1.0 | 7.0±0.7* | 8.5±1.5* |
Data are presented as mean±sem
AST: aspartate transaminase
ALT: alanine transaminase
#: 5 weeks after common bile duct ligation
*: p<0.05 versus sham-operated rats