Mean changes from run-in to end of treatment in symptom scores
| Total symptom score (0–16) | Shortness of breath score (0–4) | Chest tightness score (0–4) | Cough score (0–4) | Night-time awakening score (0–4) | |
| B/F versus placebo | −0.56 (−0.89–−0.24) | −0.21 (−0.32–−0.10) | −0.16 (−0.26–−0.05) | −0.07 (−0.17–0.03) | −0.16 (−0.27–−0.05) |
| p‐value | <0.001 | <0.001 | 0.004 | 0.180 | 0.004 |
| B/F versus B | −0.26 (−0.58–−0.07) | −0.12 (−0.23–−0.01) | −0.09 (−0.20–0.01) | −0.02 (−0.12–0.08) | −0.05 (−0.16–0.06) |
| p‐value | 0.120 | 0.040 | 0.080 | 0.651 | 0.361 |
| B/F versus F | −0.02 (−0.35–0.30) | 0.00 (−0.11–0.11) | −0.01 (−0.12–0.09) | −0.02 (−0.12–0.08) | −0.04 (−0.15–0.07) |
| p‐value | 0.891 | 0.946 | 0.788 | 0.705 | 0.463 |
| B versus placebo | −0.30 (−0.63–0.02) | −0.09 (−0.20–0.02) | −0.06 (−0.17–0.04) | −0.05 (−0.15–0.05) | −0.11 (−0.21–−0.00) |
| p‐value | 0.067 | 0.100 | 0.238 | 0.372 | 0.049 |
| F versus placebo | −0.54 (−0.87–−0.21) | −0.21 (−0.32–−0.10) | −0.14 (−0.25–−0.04) | −0.05 (−0.15–0.05) | −0.12 (−0.22–−0.01) |
| p‐value | 0.001 | <0.001 | 0.008 | 0.335 | 0.033 |
Data are presented as mean (95% confidence interval) unless otherwise stated
B: budesonide
F: formoterol