Time h | Immune cells per 100 cells in BALB/c | Immune cells per 100 cells in C57BL/6 | ||||||
M | L | N | Overall change# | M | L | N | Overall change# | |
0 | 67±3 | 33±3 | 1±0 | 0 | 76±1§ | 24±1 | 0 | 0 |
4 | 48±1¶ | 44±1¶ | 8±1¶ | 37±6¶ | 52±1¶,§ | 45±1¶ | 3±0¶,§ | 48±3¶ |
12 | 15±1¶ | 34±1¶ | 51±1¶ | 103±4¶ | 41±2¶,§ | 25±2¶ | 33±4¶,§ | 71±6¶,§ |
48 | 32±3* | 20±2* | 48±2 | 95±4 | 53±2¶,+ | 28±2 | 18±2*,+ | 45±4¶,+ |
72 | 49±2* | 30±2 | 21±3* | 41±7* | 56±2 | 30±3 | 14±3 | 40±3 |
Data are presented as mean±sem unless otherwise stated
M: macrophages
L: lymphocytes
N: neutrophils
#: the overall change represents the combined change in the numbers of macrophages, lymphocytes and neutrophils identified in lung tissue compared with the zero time point, and was used to determine the peak of immune responses
*: p<0.05 from the previous time point
¶: p<0.025 from the previous time point
+: p<0.05 between BALB/c and C57BL/6 mice
§: p<0.025 between BALB/c and C57BL/6 mice