Table 3

Comparison of age and lung function tests results in the cystic fibrosis (CF) patients with or without chronic bacterial colonisation

ColonisedYes-no
YesNo
Patients n1429
Age yrs13.7 (2.8)9.3 (3.9)2.0–6.7***
FEV1 % pred74.7 (22.8)96.1 (13.9)−32.3–−10.1***
MEF50 % pred#67.1 (36.0)110.0 (36.0)−68.3–−17.6**
MEF25 % pred#43.7 (30.9)79.1 (27.5)−55.9–−14.9**
RV/TLC %33.0 (14.4)22.7 (5.4)3.4–17.1**
MR1.91 (0.69)1.47 (0.28)0.14–0.74**
LCI9.85 (3.49)7.60 (1.37)0.76–3.74**
  • Data are presented as mean (sd) and 95% confidence interval for thedifference between the groups unless otherwise stated

  • FEV1: forced expiratory volume in one second

  • % pred: % predicted

  • MEF50: maximum expiratory flow at 50% of forced vital capacity

  • MEF25: maximum expiratory flow at 25% of forced vital capacity

  • RV: residual volume

  • TLC: total lung capacity

  • MR: mixing ratio

  • LCI: lung clearance index

  • #: MEF50 and MEF25 results were available for analyses in 20 noncolonised patients

  • : RV/TLC results were available for analyses in 22 noncolonised patients and 13 colonised

  • **: p<0.01

  • ***: p<0.001