Parameters of the nine obstructive sleep apnoea (OSA) patients and nine controls (ghrelin group)
| OSA patients | Controls | p‐value | |||
| Baseline | 2 Days of therapy | At baseline# | At 2 days# | ||
| Age yrs | 54±2 | 49±2 | 0.140 | ||
| BMI kg·m−2 | 33.0±1.4 | 33.9±1.3 | 0.644 | ||
| Body fat % | 34.5±1.6 | 35.2±1.4 | 0.730 | ||
| AHI·h sleep−1 | 55±10 | 5±2 | 3±1 | <0.001 | 0.102 |
| ODI·h−1 | 55±4 | 7±2 | 7±2 | <0.001 | 0.867 |
| Basal O2 saturation % | 92±1 | 96±1 | 95±1 | 0.018 | 0.349 |
| Minimal O2 saturation % | 67±3 | 85±2 | 85±2 | <0.001 | 0.953 |
| Average O2 saturation % | 85±2 | 91±1 | 89±1 | 0.025 | 0.047 |
| Arousals n | 61±5 | 18±1 | |||
| ESS | 12.2±0.7 | 5.0±0.3 | 5.6±0.4 | <0.001 | 0.310 |
| Plasma insulin µE·mL−1 | 11.1±1.5 | 11.1±1.1 | 14.7±1.6 | 0.129 | 0.090 |
| Somatomedin C ng·mL−1 | 131±16 | 146±17 | 148±15 | 0.465 | 0.924 |
| Plasma leptin ng·mL−1 | 9.2 (7.3–11.5) | 10.1 (8.0–12.9) | 8.5 (6.7–10.8) | 0.824 | 0.611 |
| Plasma ghrelin pg·µL−1 | 57.9 (46.0–72.9) | 19.7 (15.0–26.6) | 10.8 (7.6–15.3) | 0.001 | 0.204 |
Data are presented as mean±sem or geometrical mean (geometrical sem) unless otherwise stated
BMI: body mass index
AHI: apnoea/hypopnoea index
ODI: oxygen desaturation index
O2: oxygen
ESS: Epworth Sleepiness Scale
#: controls versus OSA