Table 3

Nonadherence according to clinical, bacteriological and radiological features, type of tuberculosis, and treatment characteristics in 70 tuberculosis human immunodeficiency virus-infected patients

AdherenceNonadherenceORp‐value
Sex (male)44 (93.6%)18 (78.3%)0.30.104
Age# yrs32.4±6.330.6±6.30.270
Drug addiction39 (83.0%)21 (91.3%)2.10.480
Presence of other illness30 (63.8%)16 (69.6%)1.30.836
Use of nucleoside analogous30 (63.8%)6 (26.1%)0.20.007
Use of protease inhibitors5 (10.6%)2 (8.7%)0.80.995
Current i.v. drug use4 (10.3%)14 (66.7%)17.5<0.001
Methadone+
 In CDP7 (19.4%)0 (0.0%)0.000.082
 Other clinics3 (9.4%)2 (9.5%)1.00.995
Multidrug resistance§3 (8.3%)4 (20.0%)2.70.234
Previous tuberculosis therapy2 (4.3%)2 (8.7%)2.10.593
Modified treatment6 (12.8%)7 (30.4%)3.00.103
Complications5 (10.6%)13 (56.5%)10.9<0.001
  • Data are presented as n (%), unless otherwise stated

  • OR: odds ratio

  • i.v.: intravenous

  • CPD: centre for ambulatory treatment of respiratory diseases

  • #: mean±sd

  • : data for the 60 patients in whom the risk was drug addiction

  • +: in comparison with no use of methadone

  • §: includes only the 56 patients in which a sensibility test to drugs had been carried out