Table 2—

Results before and after the two 4-week treatment periods

FluticasoneMontelukast
PrePostp-valuePrePostp-value
FEV1 L 2.68±0.09 3.18±0.10<0.001 2.75±0.09 3.12±0.12<0.001
PC20 mg·mL−10.178÷1.170.449÷1.17<0.0010.196÷1.180.217÷1.170.39
Sputum eosinophils % 4.9÷1.3 1.8÷1.3<0.001 3.2÷1.3 2.3÷1.40.16
Exhaled NO ppb54.8÷1.126.7÷1.1<0.00152.0÷1.148.7÷1.10.36
Tryptase pg·mL−1 8.8÷1.4 4.0÷1.4 0.005 4.8÷1.4 6.5÷1.40.28
  • Mean values and arithmetic (±) or geometric (÷) sem are given

  • FEV1: forced expiratory volume in one second

  • PC20: provocative concentration causing a 20% fall in FEV1

  • NO: nitric oxide