Table 2—

Features of experimental design

First author [ref no.]Experimental design
TypeAssessmentsBronchoconstriction starts as
Chow 25CrossoverUBMInduced by exercise
ABM
ABMP
Christensen 2Parallel groupUBMNoninduced
Dias 6Parallel groupUBMNoninduced
ABM
ABMP
Fung 26CrossoverABMPInduced by exercise
Luu 27Parallel groupUBMNoninduced
ABM
Mitchell 1Parallel groupUBMNoninduced
Morton 28CrossoverABMInduced by exercise
Tandon 29CrossoverUBMInduced by histamine
ABM
Tandon 24CrossoverUBMNoninduced
ABM
Tashkin 30CrossoverABMPInduced by methacholine
Tashkin 23CrossoverABMPNoninduced
  • UBM: unadjusted

  • ABM: adjusted by baseline measures

  • P: reported as percentage of baseline value