Table 3—

Forced expiratory volume in one second (FEV1) and exhaled nitric oxide (eNO) before and after the placebo and allergen challenge tests

Subjects nFEV1 LeNO ppbp-value#
Before challenge testAfter challenge testBefore challenge testAfter challenge test
Placebo423.28±0.813.03±0.6213.96±15.6512.64±10.700.344
Allergen challenge test0.950
 −bronchoconstriction363.23±0.772.94±0.678.44±5.898.40±5.04
 +bronchoconstriction143.33±0.592.67±0.5817.50±12.0525.82±18.240.018
 +late bronchoconstriction73.03±0.502.43±0.449.33±2.9120.41±11.67
 +low basal NO level0.012
  • Data are presented as mean±sd

  • ppb: parts per billion

  • #: significance of eNO change after challenge test in paired t-test