Table 1—

Patient characteristics

Patients n40
Sex M:F17:23
Age mean (range)42.3 (20–59)
Smoking
 Neversmokers n20
 Exsmokers# n8
 Current smokers n (pack-yrs)12 (0.8–40.5)
Atopy no:yes25:15
Specific IgE no:yes:not tested29:10:6
B-eosinophil count 109·L−1 mean (range)0.195 (0.011–0.700)
Previous asthma diagnosis no:yes13:27
Previous asthma medication no:yes13:27
PEF surveillance at work done no:yes17:23
 Complies with OA8 of 23
 Does not comply with OA5 of 23
 Different10 of 23
Baseline FEV1
 L mean (range)3.39 (2.17–4.79)
 % pred mean (range)94 (64–121)
Histamine provocation test done no:yes11:35
 PD15FEV1 ≥mg+19 of 35
 PD15FEV1 >1.6 mg+16 of 35
Protective medication during challenge no:yes48:2§
Challenge test result
 Bronchoconstriction no:yes36:14
  • M: male

  • F: female

  • Ig: immunoglobulin

  • OA: occupational asthma

  • FEV1: forced expiratory volume in one second

  • PD15FEV1: dose of inhaled histamine causing a 15% fall in FEV1

  • #: stopped smoking at least 1 yr before the examination

  • : defined as one or more positive (≥3 mm) reactions in the standard skin-prick test series

  • +: 14

  • §: patients 12 and 31