Acute change in forced expiratory volume in one second (FEV1) from pre- to 30 min post-administration of the study drug at baseline and week 4
| % Change in FEV1 | TNS | Colistin |
| Week 0 | ||
| Patients n | 51 | 62 |
| Mean±sd | −4.49±8.11 | −3.87±9.36 |
| p-value# | <0.001 | <0.001 |
| Week 4 | ||
| Patients n | 48 | 58 |
| Mean±sd | −2.57±5.39 | −2.59±9.02 |
| p-value# | 0.002 | 0.030 |
TNS: tobramycin nebuliser solution
#: within-group testing using the paired t-test