Table 3—

Multiple linear regression of change in forced expiratory volume in one second (mL·yr⁻¹) based on an average observation period of 11.5 yrs of the participants with at least two measurements of lung function

Variable	Females			Males
Variable	Estimate	sem	p-value	Estimate	sem	p-value
Intercept	69.01	8.76	<0.0001	75.8	13.0	<0.0001
Age	−2.54	0.37	<0.0001	−3.40	0.55	<0.0001
Age²	0.015	0.0037	<0.0001	0.02	0.0056	<0.0001
Smoking			<0.0001			<0.0001
No	0			0
Yes	−9.21	1.35		−12.2	2.21
BMI			0.0008			0.01
<18.5	−3.63	3.98		−11.3	11.7
≥18.5 and <25	0			0
≥25 and <30	2.09	1.55		7.37	2.22
≥30 and <35	10.2	2.61		4.02	3.78
≥35	7.97	4.12		9.03	8.13
CMH			0.18			0.006
No	0			0
Yes	−3.20	2.41		−9.03	3.28
Asthma			0.006			0.006
No	0			0
Yes	−7.33	2.68		−11.57	4.20
Diabetes			0.97			0.33
Normal	0			0
Diabetes	0.65	5.79		7.91	5.82
NewDM	−0.88	4.27		−2.46	4.67

BMI: body mass index
CMH: chronic mucus hypersecretion
DM: diabetes mellitus