Table 7—

Morbidity and lung function parameters before and during the study

Before studyDuring study
1 yr2 yrs3 yrs
Time lost from work/school days5 (4–7)3.5 (0–12)0 (0–4.75)0 (0–3.75)***,#
Primary care visits n5 (4–7)2 (1–3)1 (0–2)1 (0–2)***’#
Emergency visits n
 Primary care1 (0–3)0 (0–0)0 (0–0)0 (0–0)
 Acute care hospital1 (0–1)0 (0–0)0 (0–0)0 (0–0)
Hospitalisations n0 (0–0)0 (0–0)0 (0–0)0 (0–0)
Nocturnal awakenings n60 (24–225)10 (0–33)4 (0–11)0 (3–10)***,#
FEV1 % pred76.50 (64.75–85.50)81.50 (67.75–90)85 (70–94.50)85.50 (71.50–97)***,#
 L2.200 (1.715–2.562)2.220 (1.805–2.715)2.450 (1.850–2.850)2.360 (1.885–2.282)***,#
  • Data are presented as median (interquartile range)

  • FEV1: forced expiratory volume in one second

  • % pred: percentage of the predicted value

  • Comparison of all variables at the four time points were significant (p<0.001)

  • ***: p<0.001 for comparison at 1, 2 and 3 yrs

  • #: p=ns for comparison at 2 and 3 yrs (Friedman one-way analysis of variance)