Human leucocyte antigen (HLA) DR B alleles frequency in patients with grass-pollen allergy manifested as asthma/rhinitis, rhinitis only and in control nonatopic subjects
| Rhinitis only | Asthma/rhinitis | Control nonatopic | |
| Chromosomes n | 84 | 80 | 104 |
| DR B alleles | |||
| B1*01 | 13 (15.5) | 9 (11.2) | 7 (6.7) |
| B1*15 | 4 (4.76) | 15 (17.5)# | 13 (12.5) |
| B1*16 | 2 (2.38) | 9 (11.25)¶ | 3 (2.88) |
| B1*03 | 9 (10.7) | 5 (6.2) | 10 (9.6) |
| B1*04 | 11 (13.1) | 4 (5.0) | 12 (11.5) |
| B1*07 | 18 (21.4) | 14 (17.5) | 15 (14.4) |
| B1*08 | 2 (2.4) | 2 (2.5) | 2 (1.9) |
| B1*09 | 1 (1.2) | 0 | 1 (0.9) |
| B1*10 | 1 (1.2) | 0 | 5 (4.8) |
| B1*11 | 11 (13.1) | 8 (10.0) | 17 (16.3) |
| B1*12 | 3 (3.6) | 3 (3.7) | 9 (8.6) |
| B1*13 | 8 (9.5) | 11 (13.7) | 7 (6.7) |
| B1*14 | 1 (1.2) | 0 | 3 (2.9) |
| DR B genes/haplotypes | |||
| B 3* | 32 (38.1) | 27 (33.7) | 46 (44.2) |
| B 4* | 30 (35.7) | 18 (22.5) | 28 (26.9) |
| B 5* | 6 (7.1) | 24 (30.0)+ | 16 (15.4) |
Data are presented as alleles n (%)
#: p=0.006, p‐value corrected for incidental significance (pcor)=ns versus rhinitis group
¶: p=0.03, pcor=ns vs rhinitis group and versus nonatopic controls
+: p=0.0002, pcor=0.003 versus rhinitis group and p=0.02, pcor=ns versus nonatopic controls