Table 5—

Multiple logistic regression analysis of associations between symptoms in the first and second year of life and exposure to traffic-related air pollution in females

Exposure variableSymptom variable
WheezeCough without infectionDry cough at nightObstr./spast./asthmoid bronchitisRespiratory infections
Age of 1 yr
 Subjects n753717757761754
 PM2.5·1.5 µg·m−30.94 (0.70–1.27)1.19 (0.84–1.70)1.17 (0.81–1.68)0.98 (0.68–1.41)1.06 (0.87–1.31)1.08(0.84–1.41)
 PM2.5 abs·0.4×10−5 m−11.01 (0.74–1.37)1.25 (0.87–1.78)1.16 (0.79–1.71)0.94 (0.63–1.39)1.05 (0.85–1.30)1.06(0.80–1.39)
 NO2·8.5 µg·m−30.90 (0.64–1.28)1.22 (0.81–1.85)1.20 (0.78–1.84)0.97 (0.63–1.48)1.09 (0.86–1.38)1.09(0.80–1.47)
Age of 2 yrs
 Subjects n716710719745722
 PM2.5·1.5 µg·m−31.04 (0.83–1.30)NA1.13 (0.86–1.48)0.91 (0.68–1.21)0.98 (0.73–1.31)1.04(0.83–1.31)
 PM2.5 abs·0.4×10−5 m−11.07 (0.85–1.36)NA1.12 (0.84–1.48)0.95 (0.71–1.28)1.04 (0.75–1.43)1.06(0.83–1.34)
 NO2·8.5 µg·m−31.03 (0.80–1.34)NA1.17 (0.86–1.60)0.90 (0.65–1.25)0.98 (0.70–1.39)1.04(0.79–1.35)
  • Data are presented as # adjusted odds ratio of symptoms associated with interquartite range of air pollution variables (95% confidence intervals), unless otherwise stated

  • PM2.5: particles with a 50% aerodynamic diameter of 2.5 µm

  • NO2: nitrogen dioxide

  • Obstr.: obstructive

  • Spast.: Spastic

  • NA: not available

  • #: Adjusted for parental atopy (yes/no), maternal education, siblings (y/n), environmental tobacco smoke at home (y/n), use of gas for cooking (y/n), home dampness (y/n), indoor moulds (y/n), keeping of dogs (y/n) and cats (y/n) study (German Infant Nutrition Intervention Programme (GINI)-intervention, GINI-observation, Lifestyle Related Factors on the Human Immune System and Development of Allergies in Asthma (LISA))