Genotypic and allele frequencies at +853 and –418 loci of tissue inhibitor of metalloproteinases-;2 gene in chronic obstructive pulmonary disease (COPD) patients and control subjects
| Subjects | +853 locus | −418 locus | |||||||||
| Genotypes | Allele | Genotypes | Alleles | ||||||||
| G/G | G/A | A/A | G | A | G/G | G/C | C/C | G | C | ||
| COPD | 79 (89.7) | 9 (10.2) | 0 (0.0) | 167 (94.9) | 9 (5.1) | 54 (61.3) | 32 (36.4) | 2 (2.3) | 140 (79.5) | 36 (20.5) | |
| Control | 24 (60.0) | 14 (35.0) | 2 (5.0) | 62 (77.5) | 18 (22.5) | 33(82.5) | 6 (15.0) | 1 (2.5) | 72 (90.0) | 8 (10.0) | |
| p-;Value | 0.0001 | <0.0001 | 0.056 | 0.049 | |||||||
| Odds ratio (95% CI) | 5.4 (2.3–12.6) | 2.3 (1.0–5.2) | |||||||||
Data presented as n (%) unless otherwise stated
CI: confidence interval