Table 1—

Baseline characteristics of the total sample and subgroups according to forced expiratory volume in one second (FEV1) % pred

FEV1 % predTotal sample
79–5049–30pred<30
Patients n22252168
M:F15:716:912:943:25
Age yrs64.1±6.464.8±7.364.1±6.864.6±6.8
Disease duration6.5±5.3)7.5±5.58.2±4.27.6±4.7
FEV1 % pred60.9±9.036.4±5.022.3±5.139.9±17.0
VC % pred83.2±13.964.7±14.451.5±14.266.6±18.9
TLCO % pred47.1±25.634.3±20.920.7±12.333.9±22.5
6MWD308.6±86.8261.0±93.1207.4±83.4260.7±95.7
SGRQ total36.4±19.147.5±17.154.3±14.646.0±18.3
SIP overall4.9±6.89.9±9.310.6±7.08.5±8.1
MACL total3.1±0.83.1±0.52.9±0.53.0±0.6
  • Data are presented as mean±sd unless otherwise stated

  • M: males

  • F: females

  • VC: vital capacity

  • TLCO: carbon monoxide transfer factor

  • 6MWD: 6-min walking distance

  • SGRQ: St George's Respiratory Questionnaire

  • SIP: Sickness Impact Profile

  • MACL: Mood Adjective Check List

  • Disease duration: years since first occurrence of symptoms