Criteria for accepting twitch responses for analysis.
| For stimulations performed at relaxed functional residual capacity |
| No change in end-expiratory lung volume from resting functional residual capacity value, as reflected by esophageal pressure signal, immediately after stimulation |
| Relaxation of the diaphragm, as signalled by diaphragmatic electromyography activity |
| For stimulations performed at relaxed functional residual capacity and during the maximal inspiratory manoeuvres |
| Absence of oesophageal peristalsis at time of twitch stimulation |
| <20% variability in amplitude of CDAP of either hemidiaphragm |
| Absence of electrocardiogram superimposition on CDAP |
Adapted from 16
CDAP: compound diaphragmatic action potential