SMC phenotype | |||||
Actin markers | MHC markers | ||||
HHF-35 | CGA7 | anti-SM1 | anti-SM2 | Fibronectin | |
Cellular intimal thickening | ++ | +/− | ++ | +/− | ++ |
Intimal fibrosis | ++ | ++ | ++ | ++ | − |
Plexiform lesion | ++ | − | ++ | − | + |
Media | ++ | ++ | ++ | ++ | − |
SMC: smooth muscle cell
MHC: myosin heavy chain
++: more than two-thirds of cells positive
+: half of cells positive
+/−: <10% of cells positive
−: negative