Control | CF | p-value | |
Subjects n | 8 | 17 | |
Age yrs | 9.5±1.7 | 14.9±1.0 | 0.01 |
FEV1 % | Not measured | 77.2±7.1 | |
Total cells ×104·mL−1 BALF | 10.2±1.2 | 307±68 | 0.014 |
Neutrophils % | 0.7±0.3 | 60.8±6.4 | <0.0001 |
Lymphocytes % | 15.1±5.5 | 5.8±1.1 | 0.027 |
Macrophages % | 84.1±5.5 | 32.8±5.9 | <0.0001 |
Eosinophils % | 0.1±0.1 | 0.5±0.2 | ns |
Bacteriology | No growth | P. aeruginosa 9 | |
H. influenza 1 | |||
No growth 7 |
Results are expressed as the mean±sem for n independent determinations. Comparisons were made for continuous variables by an unpaired two-tailed t-test. FEV1: forced expiratory volume in one second; BALF: bronchoalveolar lavage fluid; CF: cystic fibrosis.