Treatment compliance and duration#
| Ciprofloxacin DPI 14 days on/off | Placebo 14 days on/off | Ciprofloxacin DPI 28 days on/off | Placebo 28 days on/off | |
| Patients n | 176 | 88 | 171 | 86 |
| Compliance % | ||||
| Mean±sd | 96.2±8.2 | 96.2±9.9 | 95.8±10.8 | 96.3±8.9 |
| Compliance ≥80% n (%) | 167 (94.9) | 82 (93.2) | 159 (93.0) | 81 (94.2) |
| Treatment duration days | ||||
| Mean±sd | 281.7±91.6 | 272.1±103.0 | 269.5±86.4 | 262.7±90.7 |
| Median | 322.0 | 322.0 | 308.0 | 307.0 |
DPI: dry powder for inhalation. #: compliance was determined after imputation of (partially) missing exposure dates as number of capsules taken/number of planned capsules. Treatment duration was assessed from first to last day of study drug intake irrespective of interruptions or off-cycles; the final off-cycle after the last dose was not included. The maximum treatment duration was 322 days for the 14-day on/off arm and 308 days for the 28-day on/off arm.