Possible clinical relevance of pulmonary haemodynamics during exercise

Decision on valve surgery/intervention: symptomatic mild mitral stenosis and low flow/low gradient aortic stenosis, asymptomatic severe aortic insufficiency and mitral regurgitation
Unmasking of abnormal physiology during exercise suggestive of occult pulmonary vascular or left heart disease or early pulmonary vascular disease in patients at risk of PAH
Diagnostic work-up of patients with known chronic pulmonary or cardiac disease, but still unexplained dyspnoea
Diagnostic work-up of pulmonary hypertension: discrimination between group 1 and group 2 pulmonary hypertension in patients with ambiguous test results
Risk stratification in PAH: assessment of prognosis
Follow-up in PAH patients: assessment of treatment efficacy (exercise capacity and right ventricular function)

PAH: pulmonary arterial hypertension.