Contraindications for bronchial challenge testing
| Airflow limitation |
| FEV1 <60% predicted (adults or children) or 1.5 L (adults) |
| FEV1 <75% predicted (adults or children) for exercise or eucapnic voluntary hyperpnoea challenge |
| Spirometry quality |
| Inability to perform acceptable and repeatable spirometry manoeuvres throughout the test procedure |
| Cardiovascular problems |
| Myocardial infarction or stroke in last 3 months |
| Uncontrolled hypertension |
| Known aortic aneurysm |
| Recent eye surgery or intracranial pressure elevation risk |
| General |
| Inability to perform any of the testing manoeuvres, such as inhaling the challenge agent consistently or difficulty with exercise on treadmill or bike; most commonly in young children or elderly patients |
FEV1: forced expiratory volume in 1 s.